[Creative PEGWorks 한국공식대리점] Hyaluronic Acid - Aldehyde

어스바이오는 Creative PEGWorks 한국 공식 대리점으로서 모든 제품을 전문적으로 취급 및 공급하고 있습니다.
Creative PEGWorks의 Aldehyde Hyaluronic Acid 제품을 소개드립니다.
 

 

Product Information:

Hyaluronic Acid is functionalized with aldehyde groups. Purity: >95% powder. Degree of substitution (DoS): 5 mol %; unless specifically noted in the catalog number. For example, HA-312-50% means that the DoS for aldehyde is 50%. HA-Aldehyde with lower or higher aldehyde substitution ratio (e.g. 1% and 10%) is available through custom synthesis service.

Properties

• Name and Source: Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. CAS# 9004-61-9
• Appearance: White, lyophilized powder, except dye-labeled HA reagents.
• Solubility: Soluble in water and the solubility data varies with MW. Higher MW results in lowered solubility. Typically solubility ranges 5-50 mg/mL, that is, 0.5%-5%. Buffered solution at pH >6 enhances solubility due to deprotonation of carboxylic acid groups and formation of carboxylate salts. HA derivatives with hydrophobic groups will lower the solubility in water, and adding alcohol or DMSO to an alcohol-water or DMSO-water mixture can dramatically improve the solubility up to 200 mg/mL (20%).
• Degree of Substitution (DoS): The standard DoS is 5% by default. Product variants with special DoS other than 5% is indicated in the product name and catalog number. For example, HA-301-30% means that the DoS is 30% for this particular product.

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